Search Documents

By Vincent Castronova, Jane Y. C. Ma, Joseph K. H. Ma, Chang-geng Mo, Carl J. Malanga

A group of bisbenzylisoquinoline (BBIQ) alkaloids has been shown to exhibit various degrees of effectiveness in preventing silicainduced fibrosis in animal models (1, 2). The capability of these drugs to interact with phosphatidycholine vesicles and rat alveolar macrophages was studied using fluorometric and equilibrium dialysis methods. The lipid binding affinity of these alkaloids was found to depend upon several structural factors including hydrophobic substitutions, the chiral configurations, and the double oxygen bridge-restricted conformation of the benzylisoquinoline moieties. Tetrandrine, which is highly effective in preventing fibrosis, showed strong binding to both lipid vesicles and alveolar macrophages. In contrast, curine and tubocurine, which have little or no effect on silicosis, exhibited only weak binding to lipid vesicles and almost no binding to cells. The moderate binding affinity of fangchinoline to vesicles and cells corresponded to a moderate effectiveness of the compound as an antifibrogenic agent. Methoxyadiantifoline, an alkaloid of unknown antifibrogenic potential, also exhibited high binding affinities for lipid and cells. In summary, this study indicates that alveolar macrophages exhibit large binding capacities for certain members of the BBIQ alkaloids. A positive correlation was observed between binding affinity to alveolar macrophages and the reported antifibrotic potency of these compounds, suggesting that the ability of these drugs to interact with alveolar macrophages may be a key step in inhibition of the progression of silica-induced pulmonary disease.

Jan 1, 1991

By Paul G. Schmidt

Exxon Minerals Co. was exploring for mineral deposits in Precambrian terranes of the US portion of the Lake Superior region in the late 1960s. Exploration drilling and other activities had been concentrated on massive sulfide prospects in northeastern Minnesota, but general exploration studies and competitor scouting were conducted in other areas of the region. These activities drew attention to Wisconsin in 1969 when it became apparent that Bear Creek Mining Co. had made a discovery near Ladysmith in the northwestern part of the state. Observation of their drill hole pattern suggested that a massive sulfide deposit, since named the Flambeau deposit (Schwenk, 1977), had been found. With this background, Exxon initiated an exploration program for Precambrian massive sulfide deposits in northern Wisconsin in 1970 (Figs. 1 and 2). Northern Wisconsin is extensively mantled by Pleistocene glacial drift and bedrock outcrop is sparse. Other than iron mines in the extensive iron formations along the Wisconsin-Michigan border and Jackson County, no significant mineral deposits were known in the Wisconsin portion of the Precambrian Shield until the discovery of the Flambeau deposit. Until the mid-1970s, the only specific published literature on the Wisconsin Precambrian consisted of old outcrop locations and descriptions in journals of the Wisconsin Geological and Natural History Survey (Chamberlain, 1882; [ ] Weidman, 1907; Hotchkiss, 1915) and the summary maps of Dutton and Bradley (1970).

Jan 1, 1991

By T. Eisele, T. Weldum, G. Rajala, H. Walqu, S. Kawatra

The throughput and energy efficiency of comminution circuits is reduced when ore characteristics change, causing bottlenecks in some portions of the circuit while leaving excess capacity in others. The results of analysis of three years of daily grinding circuit operating data for a full-scale plant has shown that the location of bottle-necks in the circuit will change depending on the nature of the feed ore. The circuit tends to be limited by the primary mill capacity when the ore hardness increases, and limited by the secondary mill capacity with softer ores. Two methods are considered for shifting load in the circuit to relieve bottlenecks by taking advantage of excess capacity in other parts of the circuit: 1) Addition of supplemental comminution operations, such as high-pressure grinding rolls, to process specific size fractions that are not handled efficiently by the primary mill; and 2) Use of screens to shift grinding load upstream from the secondary mills back to the primary mills. In the case of the plant examined in this study, it was found that 58% of the time there was sufficient excess capacity in the primary mills that the throughput of the circuit could have been increased by using screens to shift the grinding load from the secondary mills to the primary mills.

Jan 1, 2004

By Harry M. Conger

Thirty years ago, the U.S. gold mining industry was hanging on by its fingernails. Save for one great mine, the Homestake, most production was coming from copper smelters such as Kennecott and Magma. Even Homestake itself was under great pressure from rising costs and a fixed price for gold. The outlook was dim, to say the least. Today, as it has for most of the past decade, the American gold mining industry stands among the world leaders in production, and in the development of mining and mineral processing technology. What caused this dramatic change? Obviously, the freeing of the gold price was a major factor, as was the decline in South African production, but these events alone could not have created the U.S. strength we see today. It was technology, investment, and the determination of miners to build an entirely new industry that were the indispensable ingredients. The U.S. Bureau of Mines, with great foresight, had begun the research that led to heap leaching before the gold price began to rise, and Newmont had committed to build a small mill at Carlin, a move then considered quite risky. From that point, the U.S. gold mining industry was placed on lower-grade ores then being found in Nevada and elsewhere, but it was soon apparent that we would have to develop new technologies to deal with more refractory ores, carbonaceous as well as sulfide-bearing. This is now being done with considerable success. Despite its success, or perhaps because of it, the gold mining industry has come under pressure from various groups who characterize their activities as motivated by "public interest." The public interest they refer to properly include the health and safety workers and impacted communities, as well as protection of the environment, and with these concerns we miners have relatively little argument. In fact, we consider health, safety and the environment among our highest priorities, and not just because regulations may require us to do so. The argument, however, is not about the regulation of a viable mining industry, it is about a well-organized movement to attack and condemn mining in the media and to misrepresent its importance to the Nation and its willingness to accept responsible regulation. Once largely local or regional, the interest groups to which I refer are now quite large, national in scope, and even becoming international. This trend, taken together with finances raised from their dues and contributions, would make the interest groups formidable adversaries for mining, but their grip on the media enormously magnifies their influence. Unfortunately, it also makes possible the wide dissemination of incomplete, incorrect or slanted information. I am not here to "bash" the interest groups. On the whole, I believe that many of them have made positive contributions to society. As conservationists, however, I question their authority to make, or foster, decisions about which American industries and communities live and which die. To illustrate, I would like to present for your consideration the problem of cyanide, one of the issues over which the gold mining industry is most threatened. CYANIDE-POISON OR MIRACLE SOLVENT? Let me get this out of the way right up front: cyanide in most of its chemical forms is toxic. In some forms it is also listed as a carcinogen. These are adverse characteristics cyanide shares with a considerable number of industrial chemicals, including some that are widely used without the stringent regulations already in place for the mining uses of cyanide. In these uses, by the way, the risk to humans comes from direct ingestion of cyanide or cyanide-bearing solutions, or from the accidental acidification of solutions leading to release of hydrocyanic acid gas. That these risks are under control in mining can be seen from the fact that, in modern U.S. practice, there has never been a documented fatality attributed to cyanide! Because of its toxicity, cyanide cannot enter and be accumulated in the food chain. It can, however, be a threat to birds and animals that ingest cyanide-bearing solutions. Protection against this is, quite properly, a responsibility of individual mining operations, and considerable sums are spent each year to prevent or reduce bird and animal exposures. It should be evident, though, that many human activities, including highway traffic, windmills, use of pesticides and the like, result in bird and animal losses. Mining's use of cyanide, and the measures taken to protect birds and animals, should be considered in context. Cyanide must be kept out of surface streams and groundwater, and existing regulations mandate this. Any cyanide residues left in leach heaps, waste dumps and disused facilities must be eliminated, and we have proven technologies to do this now, just as we have means to detoxify tailings prior to disposal. The gold mining industry decries those rare instances when irresponsible operators fail to deal with contamination, and agrees that they should be held responsible. We do not agree, however, that the great majority of responsible companies should be punished, in advance, for accidents that have never happened. So much for the poison, what about the "miracle solvent?" Is that an overstatement? Well, consider the fact that gold has been called "noble" from earliest times, because it does not oxidize under atmospheric exposure, and that it appeared to the ancients to be utterly insoluble. Later generations of scientists did discover that it could be dissolved, but only by a combination of acids so potent that it became known as aqua Regia. Later still, it was found that chlorine would also dissolve gold, and attempts were made to base commercial processes on this, without a great deal of success. It remained

Jan 1, 1995

By Mark S. Stagg, Michael J. Nutting, Douglas R. Barlet

Single-row bench blasts at a reduced scale in the field were used to study the effects of delay time on fragmentation. Nine shots with a spacing of 21 in. and a burden of 15 in. (S/B = 1.4) and nine shots with a spacing of 30 in. and a burden of 15 in. (S/B = 2.0) were completely screened to determine particle size distributions. Delay intervals between holes ranged from 0 to 45 msec, corresponding to effective delay intervals ranging from 0 to 36 msec per foot of burden. Each shot was instrumented with strain and pressure gages to measure in situ blast dynamics and to evaluate interactions between blastholes. Finer overall fragmentation was produced for shots with delay intervals between 1 and 17 msec per foot of burden. Only for shots within this optimum delay range was it observed that the strains induced by stress waves constructively interacted with strains induced by gas pres- sure from an earlier detonated hole. Coarsest fragmentation resulted at delay intervals less than 1 msec/ft, where stress waves from each hole were observed to interact destructively, and at delay intervals greater than 24 msec/ft, where no inter- action between holes was observed, indicating a condition that can be considered as the firing of single hole shots independently.

Jan 1, 1986

By V. P. Petrov, V. S. Znamensky

There are a great number of asbestos deposits in the USSR, and some are quite large. The main deposits of chrysotile asbestos are shown in Fig. 1. The Bazhenovo deposit, which is located in the Sverdlovsk region, is the largest and has been mined since 1889. Systematic studies of asbestos deposits were begun from the very be- ginning of Soviet government and are most often connected with the names K.E. Tarasov, P.M. Tatarinov, B.J. Merenkov, N.D. Sobolev, F.V. Syromjatnikov, V.N. Lodochnikov, V.P. Petrov, V.P. Eremeev, L.A. Sokolova, V.R. Artemov, and V.F. Dybkov. Investigations by these people and others helped the USSR be one of the most important producers of asbestos in the world. In this chapter, the main asbestos deposits of the USSR are explained in a general outline from the point of view of their genesis, common features, and differences that must be taken into account for forecasting, exploration, and the mining of asbestos. All chrysotile asbestos deposits of the USSR were formed from magnesium rock as a result of comparatively low grade temperature, hydrothermal alteration, and free crystallization of fibrous chrysotile in open cavities that served as catalysts. Chrysotile, a widely distributed rock-forming mineral, is not in general an important mineral for industry as it is a long fibrous and main vein variety. However, it must serve for geologists as an important prospecting criteria. And, the geologist should search for the mineral not only in places of possible chrysotile generation, but in places where asbestos may be crystallized in its long fibers. The Soviet geologists distinguish chrysotile asbestos deposits in two groups: (1) ultrabasic rocks and (2) sedimentary dolomite terranes, taking into account how the maternal rock was affected by hydrothermal solutions. The largest deposits are related to ultrabasite. In dolomite, the largest deposits are small and their asbestos contains almost no iron, which makes it a better filler for insulating plastics. There are a few types of asbestos deposits within the limits of the ultrabasic group, the largest being a Bazhenovo type to which the deposits of the Urals are attributed. This Bazhenovo asbestos is characterized by the most complete zonality of disposition for various kinds of asbestization. These types of deposits are, for the most part, the only ones presently working in the USSR. The Bazhenovo deposit is connected to the gabbro-peridotite intrusive belt that is about 180 km long and is broken into a number of fault blocks as shown in Fig. 2. Granitoid veins of intruded rocks are found along the deepest faults, and were sources of hydrothermal solutions that affected the maternal rock. The nearest granitoid vein, ultrabasite, is substituted by listwanite that consists of quartz, talc, carbonate, and some other essentially talcous rock. The next zone of hydrothermal alteration is composed of serpentine. The boundry between serpentinite and unaltered ultrabasite is as irregular, diffuse, and rough as the boundaries between all other zones. Nearer the vein of granitic rock, ultrabasite is entirely serpentinized into massif serpentinization that penetrates through cracks and fissures. There is an unaltered ultrabasite space between fissures, and the biggest block is preserved unaltered in the central part of the massif. The Soviet geologists call this ultrabasic sopka. Preservation of the unchanged blocks is of great importance for deposit formation as volume changes are impossible during the process of asbestization and serpentinization. It may be confidently said that asbestization in Bazhenovo type deposits is possible only when alteration of ultrabasite has not completely occurred. Under conditions of massif volume, a very big mass of substance must be carried out of the ultrabasite for the progressive stage of serpentinization. However, in the regressive stage,

Jan 1, 1986

By E. A. Devuyst, G. Robbins

A unique process for removing cyanide and base metal complexes from industrial waste streams was patented by G.J. Borberly et al. (1984). The process uses SO2 (liquid or gas, or solutions of sulfite salts, or from burning elemental sulfur), plus air that is dispersed in the effluent using a well agitated vessel. Acid produced in the oxidation reactions is neutralized with lime at a controlled pH generally in the range 7 to 10. The reaction requires the presence of soluble copper as a catalyst which can be supplemented by copper sulfate if necessary. The process can be applied to the detoxification of gold and silver mining waste streams, such as carbon-in-pulp (CIP) tailing pulps, barren solution bleeds, pond waters and heap leach rinse solutions and also to plating shops wastewaters. The SO.jAir process has substantial advantages over two of the main alternative methods of cyanide destruction, namely alkaline chlorination and hydrogen peroxide. Alkaline chlorination is highly penalized in terms of reagent consumption. Chlorine is a strong oxidant reacting with species other than cyanide present in the effluent such as thiocyanate and sulfides. Furthermore alkaline chlorination is an incomplete detoxification process. Iron cyanide is not removed and the potential for harmful by-products species exist. Consequently final effluents may be subject to additional treatment in order to comply with regulatory demands.

Jan 1, 1991

By José A. Matar Ibañez

Geologic terranes in Argentina include potential mineralized environments from localized younger Precambrian cratonic outcrops through Paleozoic sequences, generally in the northwest or under younger cover, to the Mes[o] zoic-Cenozoic Andean Systems in western and southern Argentina. Argentina is self sufficient or nearly so in many metallic, nonmetallic, and energy commodities, and exploration in each of these categories is ongoing. Present production of precious metals (silver and gold) is important, and many recent discoveries of base metals, precious metals, alloy metals, and other mineral categories have been made. Economic trends, geologic environments, and commodity types important in actual exploration are described, and it is emphasized that extensive areas showing attractive alteration, geochemical, and geological anomalies, especially of porphyry, cordilleran vein, and epithermal characteristics, remain to be fully evaluated.

Jan 1, 1986

By Lars A. Stålberg

"This paper will touch several of the topics covered by SDIMI 2005, including,• Sustainability indicators for the minerals industry, • Best practice of sustainable development in the minerals industry, • Social contributions,The complex issues of a company’s "sphere of influence" and "complicity" are important to every discussion of business and Human Rights. The paper will argue that to protect and promote Human Rights needs to be regarded as an integral part of sustainable development policies for the minerals industry. This implies a need for explicit inclusion of Human Rights indicators among the indicators to be applied by the minerals industry."

Jan 1, 2005

By Brahm D. Prasad

As in other mineral deposits, variation in bitumen saturation, thickness of ore and discard occurs throughout Alberta's Athabasca Oil Sands deposit. The economic stripping ratio developed here to determine surface mineable limits takes into account capital and operating costs, crude oil prices, quality of ore, thickness of overburden, and thickness of inter-ore waste. The surface mining systems employed to remove bituminous sands (oil sands) from huge mines at depths of 60-70m use gigantic draglines, bucket wheel excavators and reclaimers, and large mobile equipment.

Jan 1, 1982

By Y. A. Attia

Auriferous sulfide ores often contain very finely disseminated gold and other precious metal particles inside the sulfide crystals. The encapsulation of precious metal particles gives rise to the refractory nature of such ores to current extraction methods. As a result, these fractions are frequently lost in the tailings. The purpose of this work was to investigate the feasibility of pretreating these refractory tailings with bioleaching before employing standard extraction techniques such as cyanidation. Leadville gold ore tailings containing auriferous pyrite were first concentrated by froth flotation. The pyrite concentrate was treated for different periods of time with 12 weeks adapted thiobacillus ferrooxidans before cyanide leaching. The bioleaching of the concentrate before cyanide leaching increased the gold extraction from 32% to 95% and that of silver from 48% to more than 98%.

Jan 1, 1987

By Sheldon P. Wimpfen

Forecasting, an ancient art, is con-ducted by everyone in varying degrees. It is a vital aspect of mineral production and conditions must be predicted over a long time frame in all aspects of the industry from exploration to plant construction. Although many government agencies as well as private industry make forecasts, there are insufficent "make good" analyses performed. The performance of more such studies could sharpen forecasting ability.

Jan 1, 1983

By M. A. Klugman

[This paper represents a portion of a lager study, concerning dispersion patterns of major, minor and trace elements in wall-rock about ore-bodies in part of the Colorado Mineral Belt. This phase of the work pertains to the Mg/Ca ratio variations in wall-rock adjacent to ore-bodies in two mines of the Alma-Horseshoe Mining District of Central Colorado. The mining district is located 80 miles southwest of Denver (Figure 1) on the east flank of the Mosquito Range. The area is typified by rugged relief with altitudes from 10,500 to 14,000 feet.]

Jan 1, 1962

By Allan M. Johnson

Dewatering is a major operational cost at sane mines. Under certain conditions, costs associated with water disposal may continue beyond the productive life of the mine. For mines with mineralized waters, this is of special concern. Since 1974 experience has been gained from the examination of a number of closed underground metal mines that exhibited drainage problems. It was observed in certain cases, that had appropriate steps been taken prior to closure, that the resulting drainage problems could have been largely avoided. The pre-closure steps would have involved alteration to the "plumbing system" of the mines: i.e., the drifts and crosscuts interconnecting the workings of the mine. This could have best been accomplished by the placement of bulkheads and/or selective drifting. In addition to reconfirming that hindsight is 20-20, a lesson learned from these case studies shows that a relatively simple hydrologic evaluation prior to mine closure may avoid a troublesome and costly drainage problem.

Jan 1, 1983

By Hans-Henrik Wallin

The stresses in the heads and shell of a grinding mill are largely dependent on the bending moment produced by the trunnion bearing. By using spherical roller bearings in a special narrow housing a short moment arm is obtained and the bending moment is reduced. For large mills a hydrostatic shoe bearing which also gives a short arm, can be used. Spherical roller bearings also require less maintenance and have a long service life. As the bearings are grease lubricated an automatic lubricator is used instead of an oil lube system. Service data from two Swedish mining companys confirm the fact that the above arrangements provide a long service life.

Jan 1, 1979

By Harold F. Yde

Hydraulic tailings fill in the Butte deep level mines was based upon studies made in 1958 by the Anaconda Company Mining Research Department, which published Bulletin No. 35, entitled "Hydraulic Stope Filling". Since then, many things have changed. At the time of the Research Departments study, dry mine tailings were hauled by rail cars from the Anaconda tailings ponds, twenty-five miles distant, to the underground mines' tailings fill plants at the Leonard Anselmo, and Mt. Con Mines. Now, with the installation of the new Weed Concentrator in Butte, tailings is delivered by pipeline to a cyclone at the Kelley Shaft, and stope filling has become more highly automated and streamlined. Presently, mill tailings at approximately thirty percent solids by weight, is pumped from the concentrator, eight thousand feet horizontally and upward, to the Kelley Fill Plant, where they are dewatered and deslimed by three Krebs Model D20B Cyclones, which discharge the material into the cased and grouted mine delivery bore holes at desired densities up to seventy percent solids. The vertical boreholes and four-inch rubber lined Victaulic pipe carry the material downward to horizontal distribution lines, which in turn tap into the stops-filling, three inch, unlined steel Victaulic pipelines. The slurry may travel several thousand feet before it finally discharges into the stope, where it lends support to the mined-out area.

Jan 1, 1969

By David. C. Hoffman

As you are all well aware, the minerals processing industry and process industries in general are now heavily involved in reassessing their process flowsheets. The topic of concern is the little arrow in one corner of the drawing at the end of the process flow that usually says "to waste." A really startling statement might have said "to waste disposal area," which implied that there was some concern, thought, or measures taken to deal with the waste. Since 1965, the year of the Water Quality Act, many laws have been passed and agencies formed dealing with the multi-faceted area of pollution. One of these laws, the Air Quality Control Act of 1967, was the initiating force in the development of Calcilox additive to help solve the problem of sludge disposal resulting from the scrubbing of SO2 bearing gases. The intent of this paper is to focus in with a wide-angle view on a particular type of waste stream, generally an aqueous, inorganic slurry, and present the reader with an alternate approach to their disposal via Calcilox additive stabilization. Each waste stream is unique and will require different techniques to meet the design objectives. Calcilox additive is not intended to be a panacea for every slurry disposal problem, but, rather a viable alternative that should be investigated before a final waste disposal approach is chosen. This paper will summarize the development of Calcilox additive; briefly discuss stabilization; and most importantly, discuss some applications to develop a feeling for Calcilox additive stabilization. Actual dollar costs will not be presented, for each waste stream differs and the ultimate disposal mode chosen greatly influences the costs.

Jan 1, 1976

By James A. Erdman

This overview briefly describes some examples of applications and difficulties in using plants that are drawn from the literature and from field experience. Because of the generally low Au concentra¬tions found in plants, the analysis of plant tissue is critical to the successful application of the biogeochemical method of prospecting. Neutron activation analysis is the most widely used method to detect Au in plants, due largely to its sensitivity; levels in the parts per billion range are easily attained. Two general types of sampling media are used in prospecting for Au: humus and living plants. Humus has been widely used in Canada, but the sampling of plants has increased there and elsewhere in recent years. The use of douglas-fir (Paeudotsuga menziesii) at a Au-bearing stockwork in Idaho is a prime example. A maximum Au concentration of 14 ppm was detected in the wood ash of this coniferous tree, well above the normal background concentration of about 0.15 ppm. Among shrubs that might be useful in Au prospecting, sagebrush or wormwood (genus Artemisia) could be sampled because it is extremely responsive to concealed mineralization. It has been used extensively in the Soviet Union and could be used in areas of the western United States where disseminated Au occurrences might be located. Among the problems one may encounter in using plants for Au prospecting are (1) physiological barriers, by which many plant species simply do not absorb Au at detectable levels; (2) misconceptions of soil-plant correlations; (3) localization of Au in plant tissue; and (4) the variation of Au concentrations due to season. Despite these limitations, biogeochemical techniques can complement or replace other geochemical methods currently used.

Jan 1, 2013

By Wilson Blake

A mathematical model based on the finite element method of stress analysis has been used to describe the behavior of the western wall of the Kimbley Pit as its slope was steepened from 45 degrees to 57 degrees. Theoretical stress changes because of slope modification are slight except at the toe of the modified slope. Magnitudes of stress created are small when compared with the strength of a competent rock. Resulting displacement patterns point out the need for determining the in situ state of stress at a site prior to excavation or modification. A comparison of model results with field measurements shows that, in general, the model has described the measured behavior of the west wall of the Kimbley Pit remarkably well.

Jan 1, 1968

By Duk-Won Park

The stability problems of back- filled spoil banks became more important since the Federal Surface Mining Control and Reclamation Act of 1977 was enacted. The material properties of spoil banks were categorized as the first part of the study and spoil slope stability was evaluated using computer programs as a second part. Emphasis was placed on the effects of natural barriers, which is required in the federal law.

Jan 1, 1982