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By Jean J. Abiassi

The Boston Marine Industrial Park (BMIP) VENT 6 project is a cut and cover tunnel, part of the Central Artery / Tunnel (CA/T) in the city of Boston. The BMIP job will serve as the south approach to the Third Harbor Tunnel crossing. The alignment is approximately 2500 Ft long and is made up of four sections starting from west to east: 1. West Tunnel 2. Boat Section 3. East Tunnel 4. Tunnel inside Vent 6 Cofferdam and connection to the Third Harbor Tunnel. The support of excavation (SOE) system for the West Tunnel, Boat Section, and East Tunnel are all a part of this project whereas the SOE for Tunnel inside the Vent 6 Cofferdam was a part of the contract for the Third Harbor Tunnel.

Jan 1, 1994

By K. N. Panigrahi

India bestowed with 6000km of the coastal belt, contains some of the richest and largest placer deposits with a mixture of heavy minerals like ilmenite, rutile, leucoxene, zircon, monazite, sillimanite and garnet. Each of the minerals is having economic value due to its inherent characteristics for industrial use in fields of paints, metallurgy, refractory, abrasive and so on. The reserves of titanium bearing minerals (ilmenite, leucoxene, and rutile) in the country is around 378 million tonnes. More than 90% of the titanium based minerals produced worldwide are utilised for making value added products in the pigment industries. Approximately 8 million tonnes of monazite reserves are available in the country from which several rare earth elements like cerium, neodymium, lanthanum, yttrium etc. can be extracted for use in several industries. The country contains a deposit of about 20 million tonnes of zircon, which is used in foundries, refractories, ceramics and chemicals. India has a reserve of 107 million tonnes of garnet and 131 million tonnes of sillimanite required for the abrasive and refractory industries respectively. Keeping in view the multifarious uses, the beach sand minerals are being exploited to have the economic growth of the nation. Although the process adopted for the separations are simple, the equipment involved are specially designed because of the nature of the material of construction. Starting from the spirals to magnetic separators, all equipments are manufactured outside India, which is not only costly, but the availability also takes much time for fulfilling the import formalities. Unlike open cast mining, beach sand mining is a environment friendly mining because dredging is implemented to cut and pump the loose sand through a slurry pump causing less damage to the surface topography as both mining and backfilling takes place simultaneously. Therefore all out efforts are made to explore the beach sand placer deposits in an economic manner to emerge as a leader in the global mineral industries.

Jan 1, 2005

By David G. Dixon, Maziar Eghbalnia

"Gold and silver nanoparticles (NPs) were deposited on pyrite at ambient temperature from colloidal solutions prepared by reduction of hydrogen tetrachloroaurate or silver nitrate by sodium sulfide or sodium tetrahydridoborate. The nanoparticles were characterized using Ultraviolet-Visible (UV-Vis) spectroscopy and the experimental spectra were fitted using Mie - Gans modeling. The modified pyrite was investigated using Electrochemical Impedance Spectroscopy (EIS). Electrodes were prepared from both natural and modified pyrite samples and were modeled using an equivalent circuit (EC) based on the EIS data. The comparison of the results revealed a decrease in charge transfer resistance for the ferric ferrous redox couple associated with the modified pyrite. From this behavior it is concluded that the electronic transport between the nanoparticles and the electrode surface over distances in nanometer scale is enhanced. Nanoparticles below a certain size act as quantum dots due to electronic confmement. Decreased charged transfer resistance at the nanometer scale may be caused by electron transport through tunneling mechanism via quantum dots.IntroductionIn recent years, considerable attention has been focused on the synthesis and study of Metal nanoparticles due to their potential applications in the fields of physics, chemistry, biology, medicine, material science and their interdisciplinary fields[!]. When material is nano-sized, the physical properties deviate markedly from those of bulk material, however, this effect is highly dependent on the particle size, interparticle distance, and morphology of the nanoparticles [2].An extremely small region of space defmed in a semiconductor material in order of nanometers is called a quantum dot, a term coined by Reed [3]. The three dimensional confinement of quantum dots can change properties of the excitons in comparison to free excitons in a bulk material [4]. Nanoparticles behave electronically as zero-dimensional (restricted in all three dimensions) quantum dots when the de Broglie wavelength of the valence electrons and the particle are in the same size range.As Reed [3] explains electrons confined in a plane have no freedom to move the third dimension. Those confined in a quantum wire are only free to move in one dimension, and those confined in a quantum dot are not free in to move in any dimension. An electron inside a cube of material IO nm on a side is confined to a point."

Jan 1, 2012

By Mani Manimaran, Inna Dymov, Mariam Melashvili, Chris Fleming, Joe O’Day

This paper presents experimental evidence that supports the use of bromine/bromide as a potential alternative to conventional cyanidation for gold leaching. The study evaluated a brominebased lixiviant, Stabilized Bromine, with considerably lower vapour pressure than liquid bromine. Using a rotating device, the rate of gold dissolution was determined at various concentrations of this reagent. The reactivity of pure pyrite, arsenopyrite and chalcopyrite minerals was also evaluated in stabilized bromine reagent. Furthermore, bromine leaching of gold in a number of gold bearing ores was undertaken. Results showed that significantly higher gold recovery can be achieved with bromine than with cyanide when leaching gold encapsulated in sulphides, but bromine consumption was high owing to simultaneous oxidation of the sulphides. The greatest promise for the bromine leach process was with oxidized gold ores. The recovery of gold from oxide ores with bromine was comparable to that achievable with cyanide and bromine consumption was reasonable when leaching was conducted at a near neutral pH of ~6. In the case of oxidized gold ores containing copper mineralization, it is possible that bromine consumption may be lower than cyanide consumption, since there is evidence to suggest that bromine is less reactive than cyanide with copper minerals.

Jan 1, 2014

THE solid nonmetallic inclusions present to some extent in all commercial steels have been variously designated. In early references they were usually called slag inclusions, and this terminology is still retained to some extent. On the premise that all nonmetallic matter produced in a metallurgical process is slag, this can be justified. We have come to think of slag, however, in a more restricted sense, and calling these particles slag inclusions is further objectionable because it fosters the erroneous concept that they are actually incorporated portions of furnace slag. Rarely is this true. The term sonims (coined from solid nonmetallic impurities) was proposed many years ago but never came into common use. In general, the term non-metallic inclusions seems to be satisfactory and adequate. NATURE AND CONS1lTUTION OF NONMETALLIC INCLUSIONS From the standpoint of origin, inclusions fall naturally into two classes: (1) those occurring as a result of reactions taking place in the body of molten or solidifying metal and (2) those resulting from mechanical incorporation of refractories or other materials with which molten steel comes in contact. The former are by far the more numerous and have been called indigenous, natural, or native inclusions. The latter are by their very nature sporadic in occurrence and have been called exogenous, accidental, adventitious, or foreign inclusions. They are often referred to as the "slag-stringer" type, though here also the material is not likely to be furnace slag. Substances Found in Inclusions. Nonmetallic inclusions are composed principally of oxides and sulfides but carbides and nitrides sometimes play an important role. In the case of indigenous inclusions the reactions by which these particles are precipitated from molten or solidifying steel may be caused by: (1) oxidation such as may occur during refining or during tapping and teeming, (2) deoxidation by added alloys, (3) change

Jan 1, 1964

By Jon R. Maki

"EVTAC, an iron ore mine in Minnesota, had trouble meeting the customer’s pellet silica requirements. In addition, the mine plan was moving towards a lower grade ore and funding was not available for plant improvements to compensate for the change in ore or improving quality. Small changes to optimize various processing equipment resulted in significant improvements in both quality and productivity; for example, productivity on one mill line increased by 10% while producing lower silica concentrate. This paper will provide the methodology that allowed EVTAC to improve quality and productivity through process optimization with little capital investment.INTRODUCTION EVTAC, an iron ore mine in Minnesota, had trouble meeting the customer pellet silica requirements. In addition, the short-term mine plan was changing to a lower ore grade. Because of limited funds, EVTAC did not have the capital for investing in the plant to compensate for the ore change or to make improvements to lower product silica levels. Small changes to optimize process equipment resulted in significant improvements in quality and productivity; for example, one mill line feed rates increased by 10% while also producing a higher quality concentrate. These changes were sufficient enough to allow the mine to lower the target ore grade beyond their initial goal. At one time, a $3M flotation facility was considered as a way to meet quality with the new ore grade. However, the process changes were able to accomplish the same silica reduction with roughly a $50,000 investment in VFDs for sump controls. This paper will discuss some of the modifications that allowed EVTAC to meet the quality and production objectives with little capital investment. It also discusses the methodology used to make these process improvements."

Jan 1, 2014

By James P. Stewart

This case history describes the engineering design and construction for the Contractor of a 35-ft-deep excavation for an 800-square-foot addition to an existing sewage pump station. The site posed unexpected geotechnical complications that included deep gravelly soil, a history of local construction difficulties, groundwater consisting of heavy salt brine, and the need to underpin the existing pump station. The project took an interesting twist when the Owner issued a change order limiting the dewatering discharge to a fraction of that required to lower the water table. This documents the interesting circumstances of this job and documents the unusual subsurface conditions in the Syracuse, NY Lakefront area.

Jan 1, 2003

(This paper reviews the reasons for and the principles followed in designing and constructing complete new surface works at the mine of the Zinc Corporation Limited, Broken Hill, New South Wales, and describes the layout, plant, buildings and services.)The Zinc Corporation mine produces high grade lead, silver and zinc sulphide ore. Lead and zinc concentrates are sent by rail to Port Pirie, where the lead is smelted and the zinc concentrate is shipped to Tasmania, England and other overseas countries.Some time ago consideration was given to the advisability of sinking an additional shaft. For some years the old main shaft had been working at full capacity and developments underground had indicated that the mine would eventually be capable of an output greater than that which could be handled through the shaft. It was therefore decided to sink a new main shaft and the site chosen was in footwall country 900 feet south of the old main shaft. The reason for the move south was so that the new shaft would be opposite the centre of gravity of the ore-bodies at depth. The size of the new shaft is 27 ft. ,6 in. x 15 ft., and the work was put in hand early in 1936.It was intended to haul the whole mine output through this shaft, which was 1,600 feet from the mill then operating. An extensive conveyor system thus became necessary unless a new mill was built near the shaft. A careful study of the situation was made by the management and consideration was given to requirements for expansion, the condition of...

Jan 1, 1940

By G. W. Luxbacher

This volume describes the use of the Penn State Mine Ventilation Simulator (PSU/MVS) to model existing mine ventilation systems and, in addition, to evaluate the effect of system modifications. Ventilation survey methods designed to insure computer input data of sufficient accuracy for simulation purposes are covered in comprehensive detail, including quantity and pressure measurement and fan performance testing. The development of input data from ventilation survey results is discussed and illustrated by the use of an actual field survey. Two programs, written in FORTRAN IV with WATFIV, are presented to calculate airway head losses from altimeter pressure measurements. An existing coal mine ventilation system is analyzed and modifications to the system are simulated and evaluated. In addition the application of the PSU/MVS to non-coal mines is briefly discussed. An extensive bibliography on ventilation surveying and simulation is included.

Jan 1, 1977

By G. Winkel

Safety conditions in industry have greatly improved over time. However, around the world, in Canada, and in each province or territory, people are still the victims of serious industrial accidents. The increasing safety of people at work then continues to be an imperative in industry today.<p> So how do we achieve a workplace where no one gets hurt? Well, in simple terms, folks need to be protected from unplanned exposures to equipment or energy sources that can do harm. If you think about it, all of our efforts in loss management and safety should then be directed toward avoiding these uncontrolled events. And it works! Our safety performance over the years has enjoyed tremendous improvement due to this support for loss management and safety. We now explore best practices toward achieving that next step in safety improvement.<p> As shown following, a large combination of loss management activities act together to support safety performance. Many of these activities are interrelated and some people have described them as the ?inputs? into an approach or program for achieving safety. Using this description, it follows that the ?outputs? of the program are some of the advertised measures of safety we see around us today, such as injury frequency rates. <p> It is asserted that a leadership focus to regularly measure safety and loss management activites (so-called ?inputs?), as a basis for taking supportive actions to ensure their effectiveness, is the basis for safety results (so-called ?outputs?) that consistently achieve high standards of excellence.<p> The concept of managing input activities, as enabled by effective measurements, can significantly act to transform our focus and priorities in the workplace. Supporting input activities like strategies, plans, or procedures with our best efforts will get us to our intended goals. Tracking outputs alone will not.<p> Safety and production have traditionally been cast as competing objectives. When both objectives are mutually supported and considered, however, people will invent ways of doing work that support both safety and production, and any other business parameter. When done right, innovation through meaningful involvement of affected people in the workplace will support safety excellence in a manner that in turn improves business efficiency overall.<p> For a workplace to be safe, it then requires everyone?s help and participation to make it happen, a collaborative effort by management, leaders, and frontline folks with the power and responsibility to take appropriate action at every level in the organization. In this way, everyone becomes a leader in safety.<p> The achievement of commitment to loss management input activities by folks in the workplace is the basis for attaining safety excellence. A workplace founded on commitment supports a safety culture with a vision for safe work performance at outstanding or world-class levels of achievement.<p> One may ask if injury incidents will be eliminated with this commitment and focus on workplace safety? Well, despite our best efforts in this area, there is never a guarantee that things can?t go wrong. We are simply not perfect. There remains in our workplace complexities and unanticipated risks that can have disastrous consequences if not managed at every moment. And when it goes wrong, we need to know we?ve truly tried our best, and now we have more to learn so we can get even better. <p> That?s the challenge represented by the safety imperative, a challenge to take safety performance that next step, a fulfillment of our commitment to the moral obligation we have to each other?s safety. It?s an effort that will continually raise the bar of world-class safety performance achievement for future generations. It?s a legacy we can be proud to be part of.

Sep 1, 2004

By Alain E. Holeyman

After scoping out the objectives of this general report, the report reviews the three assigned main themes addressed by the papers submitted to the session: pile monitoring, testing, and data processing. It focuses on later developments and on issues requiring clarification, thereby identifying topics for potential discussion. Pile Monitoring does not bring much novelty, except for the integration of IT on construction sites. As far as testing, new developments focus on internal pile loading procedures while more confidence is being gained with dynamic and kinematic load tests. Significant advances are noted in the interpretation of data, where variability of results are coped with, loading rate effects are being better addressed, and more routine use of Finite element analyses are observed. Several many older problems remain while new issues emerge from more recent technologies and approaches.

Jan 1, 2006

The 21st Annual American Mining Hall of Fame Awards Banquet sponsored by the Mining Foundation of the Southwest will be held at the Sheraton Tucson Hotel in Tucson, AZ on Saturday, Dec. 6, 2003. This year’s inductee, guest of honor and featured speaker at the banquet will be Thomas J. O’Neil, recently retired president and chief operating officer of Cleveland Cliffs Mining. Prior to Cliffs, O’Neil spent 10 years with Cyprus Minerals. He was also professor and head of the Department of Mining and Geological Engineering at the University of Arizona. As representatives of mining heritage, the Hall of Fame will induct James Boyd and Thomas F. Walsh. Walsh discovered a rich gold telluride vein in Ouray, CO, which became the Camp Bird gold mine. Boyd was a former director of the U.S. Bureau of Mines, vice president of Kennecott Copper and later president of Copper Range.

Jan 1, 2003

By James C. Barker

A uniquely mineralized area extends from northwestern Canada through Alaska into eastern Siberia. Some of the metals found there are relatively rare in the conterminous United Stales. Among these are cobalt, the platinum-group metals, and chromite. Geologic evidence suggests that cobalt and the platinum-group metals may be present in deposits that could constitute nationally important reserves. Chromite in potentially minable deposits is known, but it may be relatively less abundant. Limited reserves of these metals have been delineated, but most of the favorable terranes and reported occurrences throughout the vast expanse of Alaska remain unexplored. As part of the mineral studies mandated under the Alaska National Interest Lands Conservation Act, the Bureau of Mines&apos; Alaska Field Operations Center and the Bureau&apos;s research centers at Albany, Oreg., and Reno, Nev., are cooperating in a long- range program to investigate occurrences and delineate reserves of cobalt, the platinum-group metals, and chromite in Alaska. Studies of other critical and strategic minerals will be phased in during succeeding years, as ongoing projects are completed. This first in a series of annual reports summarizes available information about deposits and past production of cobalt, the platinum-group metals, and chromite, and describes current and planned Bureau investigations of these minerals.

Jan 1, 1981

By A. D. Storrie

An underground wet shotcrete trial was completed last year to determine the effectiveness of wet shotcrete as an alternative support mechanism to dry shotcrete in the kimberlite environment. The wet shotcrete was manufactured at the underground batch plants, transported to site using an agiecar and transferred to the shotcrete pump. The wet shotcrete is pumped to the nozzle where compressed air at 7 bar and an accelerator, Meyco SA 160, is added and enables the shotcrete to be placed successfully onto the tunnel wall. No tunnel guard was previously placed on the sidewall and hangingwall. Geotechnical testing indicates that the Grace fibre performed extremely well with the energy absorption tests at 7 kg/m3and 8kg/m3where both achieved over the mine requirement of 750joules. The Grace fibre and wet shotcrete mix also achieved a compressive strength in excess of 55 MPa, well above the 45 MPa requirement for Premier Mine. The recommended wet shotcrete mix design is therefore based upon: [Material/ CriteriaQuantity/m3Units ?Lafarge 42.5 Duratech500kg ?Condensed silica fume40kg ?Rayton Sand1.558Ton ?Delvocrete stabilizer 103.6litres ?Glenium 27CH5.4litres ?Meyco TCC 7355litres ?Water230litres ?Meyco SA16025litres ?Fibre8kg ?Cement/Water Ratio2.35? ?Water/Cement Ratio0.43? ?Flow615 mm] If the wet shotcrete system is implemented there is a potential for Premier Mine to make major savings. In South Africa there are two suitable wet shotcrete machines available for the mining industry, the Spreymec, manufactured by Tamrock and the Fermel/Meyco wet shotcrete machine. The Spreymec is a fully imported machine. The Fermel component is manufactured in South Africa and the Meyco shotcrete components are imported and supported by MBT (Master Builder Technologists) in South Africa. The Fermel/Meyco machine is assembled in South Africa. Premier Mine has allocated some R2, 100,000 towards the implementation of the wet shotcrete system. If implementation is successful there should be an internal rate of return gain of 76% with regard to this project.

Jan 1, 2001

By R Salmon, C Jones

This paper examines the recent trend towards sustainability reporting and the application of the Global Reporting Initiative (GRI) æSustainability Reporting GuidelinesÆ. It also reviews reporting in the context of the Australian Minerals Industry Code for Environmental Management, as well as the status of public sustainability reporting globally in the minerals industry. The public reporting of environmental, health and safety, social/community and economic performance has evolved over the past two decades. Initially, separate and to some degree disparate documents were produced to report performance in each distinct area. In the early to mid 1980Æs some organisations had begun to report their environmental performance through some minor commentary in their annual financial reports or through ætokenisticÆ leaflets, often used as public relations exercises. Due to more media coverage and an elevated level of public scrutiny, organisations are no longer merely reporting their good performance, but also their bad and indifferent performance. In recent years these once separate environment, health and safety and community public reports have further evolved to become more integrated, reflecting organisations embarking on the reporting of their progress towards sustainable development. The primary factor in driving the evolution of sustainability reporting has been the increasing influence of stakeholders. Two groups of external stakeholders that have had a significant influence over public sustainability reporting in recent years have been non government organisations (NGOs) and socially responsible investment funds. Significant expenditure is involved in the preparation and publication of a sustainability report however many organisations do not appear to have examined in detail what they are really trying to achieve from their public reporting process. It is important to establish objectives for the public reporting process to achieve maximum benefits. Without a framework of public reporting objectives, the benefits of the reporting process to the organisation will not be recognised and the considerable expenditure involved will be increasingly difficult to justify. We believe that by focussing on the process rather than the document, significant benefits to the organisation can be gained. Indeed, with a proper framework of objectives and targets, the reporting process can be used as a vehicle to drive organisational change, implement management systems and improve performance. An idealised framework for a public sustainability reporting process sees the organisationÆs sustainability policies drive the entire process and determine the sustainability objectives. Specific targets are then set to realise those objectives. The targets will govern performance indicators that should be used to measure the success of target achievement and which will also define what data need to be collected. Evaluation is a key component of the reporting process to measure the success of target achievement and progress in realising objectives, as well as review the need for new targets to be set. The actual production of a public document is only one, albeit important, component of the overall reporting process. The challenges that lie ahead for sustainability reporting primarily relate to the integration of environmental, social and economic performance reporting as organisations integrate their approach to these areas. This will only happen as the culture of an organisation changes to not only accept the principles of sustainable development but to implement those principles in daily operations. The reporting process has the potential to drive that cultural change by communicating the organisationÆs sustainability objectives and setting challenging targets for their realisation. Public sustainability reporting will only achieve its maximum value when it forms an integral part of an organisationÆs sustainability management system and culture.

Jan 1, 2002

By Jean Cayouette

"In 1995, Louvicourt Mine started one of the first paste backfill operations in Canada. From 500,000 tonnes in 1995, the annual paste backfill tonnage produced reached 800,000 tonnes in 1999. The maximum throughput of the surface plant (including binders) is 3,50Ot/d with a final density of 75 to 76% solids which gives a slump of 15 to 17cm. Following the start-up of the paste backfill plant, the backfill strength performance levels were well below the pilot plant’s predictions. The introduction of ferrous slag, laboratory tests on various binder ratios with or without additives, and the desliming of the tailings enabled us to optimize the mix and operation costs. Primary and secondary stopes are filled respectively with a paste containing 4.5% and 2% binders consisting of a mixture of 20% cement and 80% ferrous slag. In certain stopes, the binder ratio may vary from 2 to 7%, but always in a ratio of 80/20. Six years after start-up, or 4.5mt of paste backfill later, this paper discusses the present operation and the major changes that have occurred over the years to optimize both the operation and the paste fill quality.INTRODUCTIONLouvicourt Mine is operated by Aur Resources Inc. which owns 30% of the shares. Its partners are Novicourt Inc. (45%, subsidiary of Noranda Inc.) and Teck Corporation (25%). The mine is located in the north-west part of Quebec, about 600 km north of Montreal and about 25 km east of Val d’Or. The mine commenced commercial production in July 1994."

Jan 1, 2002

By Rusdian F. Kayadoe, Michael B. Hutahaean, Sandi A. Firmanulhaq

Deep Mill Level Zone (DMLZ) mine is located in Papua, Indonesia operated by PT Freeport Indonesia (PTFI) with approximately 1,500m below surface. The ore body extend 1230m width from northwest to southeast by 300–400m length east-west. The mine currently produces at full production of 80,000 tons per day until 2041. Part of the extension of current active production block and mitigation sits 225 m above the production block 1 (PB1) and 2 (PB2A and PB2B) which located in 2590L, named production block#4 (PB4W and PB4E). As the mining continues at PB1N, PB2A, and PB2B, the cave growth vertically and laterally to south perimeter of the footprint affecting the integrity of PB4W/E footprint. Currently, PB1N and PB2N are in active production whilst PB4E development continues from South against PB1N cave, as can be seen in Figure 1. A slight overlapping between PB1E and PB4E intentionally to promote cave connections between the two caves. Despite low stress model in the PB4E near existing caves, the PB4E cave propagation expected by the large strain and will be propagating in tension failure to the PB1E cave. Hence, designing the drill drives edge and first drawbell location as close as possible to the PB1E cave is necessary to guarantee cave connection. Since PB4 footprint development commenced in December 2021, there have been a substantial cave propagation observed from existing downhole monitoring. As the PB4 footprint designed perpendicular to existing DMLZ PB1 cave, adjustment of the development edge design is necessary to reflect the progression the loosening zone propagation to the South. Final life of mine design for extraction, undercut and ventilation level were decided in October 2023 considering latest update cave (fractured/ yielded) boundary. Numerical model of potential rock mass damage also aids the decision to locate the drift edge design. Predicting the cave progression impact is critical to both production at the existing active blocks and development of the new area. The use of cave shape data from year 2021–2023 gives an insight of the cave shape estimation at the end of 2024 when the undercut drift will be developed. This paper presents actual cave growth of active production blocks and its relative vertical progression impact as the result of drawing in order to plan for acceptable rate and provide mitigation once the minimum acceptable rock mass condition and minimum pillar threshold achieved.

Feb 1, 2025

By Y. H. Cheng, D. M. Lewis, V. Castranova, M. W. Barger, J. K. H. Ma, J. Y. C. Ma, W. F. Xin

Bis-basic ethers off fluorene and fluoren-9-substituted derivatives such as tilorone have been reported to inhibit silica-induced fibrosis in rats. The potential antifibrotic potency of 2,7-bis (diethylamino) ethixy fluorine fluorenone (F-9-H.H), fluorenoxime (F-9-one), and fluorenol (F-9-ol) was F-9-axime > F-9-one ~ F-9-H,H > F-9-ol. Since the release of reactive oxygen species and growth factors from alveolar macrophages (AM) in response to silica exposure has been linked to the development of pulmonary fibrosis, the present study was carried out to determine the inhibitory effects of these compounds on rat AM activity in vitro. The following parameters were monitored: (1) cellular viability; (2) zymosan-induced respiratory burst activity (superoxide and hydrogen peroxide release, chemiluminescence, and oxygen consumption) of AM; (3) drug binding to AM; and (4) lipopolysaccharide (LPS)-stimulated interleukin- I (IL-1) release from AM. The bis-basic ethers, at 40 did not affect cell viability when incubated with AM for 30 min, but significantly inhibited zymosan-induced macrophage respiratory burst activity. The inhibitory effect of these agents was F-9-oxime > F-9-one ~F-9-H,H > F-9-ol. Binding of these drugs to AM was time and dose dependent, and exhibited the following binding affinity: F-9-oxime > F-9-one > F-9-H,H > F-9-ol. F-9- oxime was shown to inhibit LPS-stimulated IL-I release by AM in a dose-dependent manner. This inhibition of IL-1 release by AM cannot be explained as a decrease in viability. In addition, these drugs were also shown to impair human fibroblast proliferation in response to serum stimuli without impairing cell viability. These results indicate a positive correlation between drug binding to AM or other cell types and their inhibitory effects on cellular activities including oxygen consumption, superoxide release, hydrogen peroxide secretion, chemiluminescence, IL-I release, and proliferation. The ability of-these bis-basic ethers to modify AM and fibroblast functions in vitro suggests that further investigation of their reported antifibrotic potency in vivo is warranted.

Dec 1, 1996

By Sarah Holtz Wilson, Kenneth Rossi, Carl R. Handford, David F. Tsztoo

The East Bay Municipal Utility District’s Claremont Tunnel is an 18,000-foot long water tunnel that crosses the Hayward Fault zone near Oakland, California. It was originally completed in 1929. This project involved the construction of a bypass tunnel through the fault zone, including an enlarged vault section designed to accommodate up to 8.5 feet of horizontal offset. Ground conditions encountered included sheared and crushed serpentinite and clayey fault gouge, and presented specific challenges for construction. A special excavation and support sequence used concrete-backfilled side drifts as foundations for the vault steel sets. It also allowed for a 20-foot-wide top heading and bench excavation in soft and squeezing ground conditions.

Jan 1, 2007

By M. Hopf, E. Rossouw

Keywords: Pyrometallurgy, furnace, copper coolers, freeze lining, monitoring, Saveway The use of water-cooled copper components as sidewall elements of submerged arc furnaces and other pyrometallurgical applications has become increasingly common. The high cooling efficiency of copper has made it possible to increase the service life of furnace refractories when compared to conventional refractory linings. However even the self-healing effect of ?freezing? worn areas of the lining does not necessarily protect the copper coolers against wear or corrosion completely. In order to avoid furnace explosions, various methods have been used to monitor the wear of coolers. Unfortunately, these have not been able to consistently identify localized wear. Thos Begbie (South African) and SAVEWAY (German) jointly developed technology to embed a line sensor into the copper cooler during the casting process. This system allows an exhaustive monitoring of the copper cooler. A SAVELINE sensor is placed inside the copper-cooling panel between the water-cooling passage and the hot face of the panel. The sensor follows the meandering shape of the cooling water channels. In the first instance, the sensor provides analogue information as the thickness of the copper reduces. Secondly, this wear signal will be confirmed by a signal of interruption if the sensor is washed away. Because of the structure of the sensor, a self-diagnosis is possible and indications can be confirmed (double proofed). Subsequent to the manufacture of some test pieces, coolers for a large submerged arc furnace were manufactured. The sensorized coolers have been installed at the intermittent surface (slag line) where the largest amount of corrosion has been encountered. The system has been operating since December 2005 in what is considered one of the largest submerged arc furnaces in South Africa.

Jan 1, 2006